3-氯-5-甲氧基-2-(3-氯-4-甲氧基苯基)-2H吲唑合成路线 （共 2 条）
反应条件
1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate; sodium t-butanolate in toluene
T=90°C; 15 h;
参考文献
De Angelis, Meri; Stossi, Fabio; Carlson, Kathryn A.; Katzenellenbogen, Benita S.; Katzenellenbogen, John A.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 4 p. 1132 - 1144
反应条件
1.1: NaHMDS / tetrahydrofuran / 1.25 h / 0 - 20 °C
1.2: 48 percent / tetrahydrofuran / 1 h / 20 °C
2.1: 35 percent / Pd(OAc)2; dppf; NaOtBu / toluene / 15 h / 90 °C
View Scheme
参考文献
De Angelis, Meri; Stossi, Fabio; Carlson, Kathryn A.; Katzenellenbogen, Benita S.; Katzenellenbogen, John A.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 4 p. 1132 - 1144
