反应条件
1: (5-bromo-4-methoxy-pyridin-2-yl)dimethylamine With n-butyllithium in tetrahydrofuran; hexane; toluene
T=-65°C; 0.75 h;
2: tri-isopropoxy-borane in tetrahydrofuran; hexane; toluene
T=-65 - 20°C;
3: With hydrogenchloride in tetrahydrofuran; hexane; water; toluene