[6-(二甲基氨基)-4-甲氧基-3-吡啶基]硼酸合成路线 （共 1 条）
反应条件
1: (5-bromo-4-methoxy-pyridin-2-yl)dimethylamine With n-butyllithium in tetrahydrofuran; hexane; toluene
T=-65°C; 0.75 h;
2: tri-isopropoxy-borane in tetrahydrofuran; hexane; toluene
T=-65 - 20°C;
3: With hydrogenchloride in tetrahydrofuran; hexane; water; toluene
参考文献
NEUROGEN CORPORATION; AVENTIS PHARMACEUTICALS INC.
Patent: WO2005/23806 A2, 2005 ;
Location in patent: Page/Page column 54-55 ;
WO 2005/023806 A2
