N-叔丁氧羰基-D-2-哌啶甲酰胺合成路线 （共 3 条）
反应条件
ammonium chloride; N-ethyl-N,N-diisopropylamine; HATU in DMF (N,N-dimethyl-formamide) T=0 - 20°C; 18 h;
参考文献
AstraZeneca AB
Patent: WO2005/115986 A1, 2005 ;
Location in patent: Page/Page column 103 ;
WO 2005/115986 A1
反应条件
Lawesson's reagent in 1,4-dioxane T=20°C;
参考文献
Andjelkovic, Mirjana; Ceccarelli, Simona M.; Chomienne, Odile; Mattei, Patrizio
Patent: US2008/300279 A1, 2008 ;
Location in patent: Page/Page column 9 ;
反应条件
triethylamine; trifluoroacetic anhydride in tetrahydrofuran T=0°C; 1 h;
参考文献
SHIONOGI and CO., LTD.
Patent: WO2006/116764 A1, 2006 ;
Location in patent: Page/Page column 121; 151 ;
