4,5-二氯-1H-吡咯-2-羧酸乙酯合成路线 （共 2 条）
反应条件
chlorine; acetic acid
参考文献
Rane, Rajesh A.; Telvekar, Vikas N.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 19 p. 5681 - 5685
反应条件
1: With lithium hydroxide; water in tetrahydrofuran
T=20 - 50°C; 8 h;
2: With hydrogenchloride in tetrahydrofuran; water
pH=2;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2005/26149 A1, 2005 ;
Location in patent: Page/Page column 91 ;
WO 2005/026149 A1
