反应条件
1: With trichlorophosphate in N,N-dimethyl-formamide
T=0 - 60°C; pH=7;
2: With sodium hydrogencarbonate in water; N,N-dimethyl-formamide
参考文献
KARYOPHARM THERAPEUTICS, INC.; SHECHTER, Sharon; KAUFFMAN, Michael; SANDANYAKA, Vincent, P.; SHACHAM, Sharon
Patent: WO2011/109799 A1, 2011 ;
Location in patent: Page/Page column 225 ;
