4-(1-羟基乙基)苯甲酸甲酯合成路线 （共 18 条）
反应条件
methyl-diethoxy-silane; ferrous acetate in tetrahydrofuran T=65°C; 19 h;
参考文献
Zhao, Qiwu; Curran, Dennis P.; Malacria, Max; Fensterbank, Louis; Goddard, Jean-Philippe; Lacote, Emmanuel
Synlett, 2012 , # 3 p. 433 - 437
反应条件
1: in tetrahydrofuran; diethyl ether T=-78 - 20°C; 16.25 h; 2: With water; ammonium chloride in tetrahydrofuran; diethyl ether
参考文献
WO2009/5646 A2, ;
Page/Page column 159-160 ;
WO 2009/005646 A2
反应条件
potassium fluoride; palladium diacetate; chlorobenzene in tetrahydrofuran; water T=20°C; 1 h; Inert atmosphere;
参考文献
Organic Letters, , vol. 13, # 4 p. 584 - 587
反应条件
aluminium trichloride; tert-butylamine borane in dichloromethane T=0°C; 2 h;
参考文献
Journal of Organic Chemistry, , vol. 54, # 2 p. 491 - 494
反应条件
1: With zinc diacetate in tetrahydrofuran T=65°C; 0.166667 h; 2: With methyl-di(n-propoxy)silane in tetrahydrofuran T=50°C; 48 h; 3: With hydrogenchloride; water T=0°C; 1 h;
参考文献
Synlett, , # 2 p. 253 - 256
反应条件
1: With MoVIO2(acetylacetone)2; 1,1,3,3-tetramethyldisiloxane; triphenyl-phosphine oxide in toluene T=100°C; 24 h; Inert atmosphereSealed tube; 2: With tetrabutyl ammonium fluoride in tetrahydrofuran; toluene 2 h; Inert atmosphere;
参考文献
European Journal of Organic Chemistry, , # 36 p. 7400 - 7406
反应条件
tert.-butylhydroperoxide; Rh2(Msip)4 in water T=20°C; 20 h;
参考文献
European Journal of Organic Chemistry, , # 16 p. 3088 - 3092
反应条件
dichloro bis(acetonitrile) palladium(II); Ru2(CO)4(μ-H)(C4Ph4-COHOC-C4Ph4); water; p-benozquinone in methanol; isopropyl alcohol T=85°C; 36 h; Inert atmosphereGlovebox; regioselective reaction;
参考文献
Yang, Yongsheng; Guo, Jiayi; Ng, Huimin; Chen, Zhiyong; Teo, Peili
Chemical Communications, 2014 , vol. 50, # 20 p. 2608 - 2611
反应条件
in hexane; ethyl acetate
反应条件
triethylsilane; CoP; oxygen in dichloromethane; isopropyl alcohol 3 h; Ambient temperature;
参考文献
Chemistry Letters, , # 7 p. 1381 - 1384
