(1S,2S)-N-甲基-1-苯基-1-{[(10R)-10-(三甲基硅烷基)-9-硼杂双环[3.3.2]癸-9-基]氧基}-2-丙胺合成路线 （共 8 条）
反应条件
in diethyl ether T=-78 - 20°C;
参考文献
Organic Letters, , vol. 7, # 24 p. 5397 - 5400
反应条件
in acetonitrile
T=81°C; 15 h;
参考文献
Hernandez, Eliud; Soderquist, John A.
Organic Letters, 2005 , vol. 7, # 24 p. 5397 - 5400
反应条件
in acetonitrile
6 h; Heating;
参考文献
Munoz-Hernandez, Lorell; Soderquist, John A.
Organic Letters, 2009 , vol. 11, # 12 p. 2571 - 2574
反应条件
in acetonitrile
T=81°C; 4 h; Title compound not separated from byproducts;
参考文献
Hernandez, Eliud; Soderquist, John A.
Organic Letters, 2005 , vol. 7, # 24 p. 5397 - 5400
反应条件
1.1: tert-butyllithium / tetrahydrofuran; pentane / 1 h / 0 °C
1.2: diethyl ether; tetrahydrofuran; pentane / 0.5 h / -78 °C
1.3: trimethylsilyl triflate / diethyl ether; tetrahydrofuran; pentane / -78 - 20 °C
2.1: 1.23 g / tetrahydrofuran / 3 h / -78 °C
3.1: 70 percent / acetonitrile / 15 h / 81 °C
View Scheme
参考文献
Hernandez, Eliud; Soderquist, John A.
Organic Letters, 2005 , vol. 7, # 24 p. 5397 - 5400
反应条件
1: 97 percent / hexane / 10 h / Heating
2: 38 percent / acetonitrile / 6 h / Heating
View Scheme
参考文献
Burgos, Carlos H.; Canales, Eda; Matos, Karl; Soderquist, John A.
Journal of the American Chemical Society, 2005 , vol. 127, # 22 p. 8044 - 8049
反应条件
in acetonitrile
T=81°C; 9 h;
参考文献
Hernandez, Eliud; Soderquist, John A.
Organic Letters, 2005 , vol. 7, # 24 p. 5397 - 5400
反应条件
1: 1.23 g / tetrahydrofuran / 3 h / -78 °C
2: 70 percent / acetonitrile / 15 h / 81 °C
View Scheme
参考文献
Hernandez, Eliud; Soderquist, John A.
Organic Letters, 2005 , vol. 7, # 24 p. 5397 - 5400
