trifluoroacetic acid in water T=20°C; 2 h;

1,4-diaza-bicyclo[2.2.2]octane in dichloromethane T=20°C; 4 h;

1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 20 °C 2: hydrogenchloride / tetrahydrofuran; water / 2 h / 20 °C 3: 1,4-diaza-bicyclo[2.2.2]octane / dichloromethane / 4 h / 20 °C View Scheme

hydrogen; palladium on activated charcoal in ethanol Ambient temperature;