反应条件
1: 5-Bromo-1H-pyrrolo[2,3-b]pyridine With n-butyllithium in tetrahydrofuran; hexane T=-70°C; 1 h; Inert atmosphere; 2: formic acid methyl ester in tetrahydrofuran; hexane T=-70 - 20°C; Inert atmosphere;
参考文献
F. HOFFMANN-LA ROCHE AG; ALIAGAS-MARTIN, Ignacio; CRAWFORD, James John; MATHIEU, Simon; RUDOLPH, Joachim; LEE, Wendy
Patent: WO2013/92940 A1, 2013 ;
Location in patent: Page/Page column 40 ;
