1H-吡咯并[2,3-b]吡啶-5-甲醇合成路线 (共 3 条)
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=0°C; 12 h; Heating / reflux;
参考文献
VERTEX PHARMACEUTICALS INCORPORATED
Patent: WO2005/28475 A2, 2005 ;
Location in patent: Page/Page column 142-143; 222 ;
WO 2005/028475 A2
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=-78 - 20°C; 2: With methanol in tetrahydrofuran
参考文献
WO2008/51494 A1, ;
Page/Page column 166 ;
反应条件
pyridinium chlorochromate in dichloromethane T=20°C;
参考文献
SIGNAL PHARMACEUTICALS, LLC
Patent: WO2008/51494 A1, 2008 ;
Location in patent: Page/Page column 166 ;