1-(4-氟苯基氨基甲酰基)环丙烷羧酸合成路线 （共 13 条）
反应条件
1: N,N-dimethyl-formamide; tetrahydrofuran 2: potassium carbonate / water; tetrahydrofuran View Scheme
参考文献
US2012/252840 A1, ;
US 20120252840 A1
反应条件
1: oxalyl dichloride / N,N-dimethyl-formamide; tetrahydrofuran / 25 °C 2: potassium carbonate / water; tetrahydrofuran / 0.33 h / 30 °C 3: water / butanone; water / 6 h / 20 - 74 °C View Scheme
参考文献
EXELIXIS, INC.; AFTAB, Dana, T.; CLARY, Douglas
Patent: WO2013/43840 A1, 2013 ;
反应条件
1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in isobutyramide
T=20°C; 3 h;
参考文献
EXELIXIS, INC.
Patent: WO2005/30140 A2, 2005 ;
Location in patent: Page/Page column 205 ;
WO 2005/030140 A2
