4-[[[4-(3-吡啶基)-2-嘧啶基]氨基]甲基]苯甲酸甲酯合成路线 （共 3 条）
反应条件
1: lithium hydroxide hydrate; water / 24 h / 20 °C 2: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate / N,N-dimethyl-formamide / 24 h / 20 °C View Scheme
参考文献
Marson, Charles M.; Matthews, Christopher J.; Yiannaki, Elena; Atkinson, Stephen J.; Soden, Peter E.; Shukla, Lena; Lamadema, Nermina; Thomas, N. Shaun B.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 15 p. 6156 - 6174
反应条件
in isopropyl alcohol
20 h; Reflux;
参考文献
Marson, Charles M.; Matthews, Christopher J.; Yiannaki, Elena; Atkinson, Stephen J.; Soden, Peter E.; Shukla, Lena; Lamadema, Nermina; Thomas, N. Shaun B.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 15 p. 6156 - 6174
反应条件
water; lithium hydroxide hydrate
T=20°C; 24 h;
参考文献
Marson, Charles M.; Matthews, Christopher J.; Yiannaki, Elena; Atkinson, Stephen J.; Soden, Peter E.; Shukla, Lena; Lamadema, Nermina; Thomas, N. Shaun B.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 15 p. 6156 - 6174
