N-[4-(2,4,6-三甲基苯基)-2-噻唑]-4-吡啶羧酰胺合成路线 （共 3 条）
反应条件
1: isonicotinic acid With 1,1'-carbonyldiimidazole in dichloromethane T=20°C; 2 h; 2: 4-(2,4,6-trimethylphenyl)thiazol-2-ylamine in dichloromethane T=20°C;
参考文献
Lau, Johnson; Huang, Jiann-Jyh
Patent: US2011/230486 A1, 2011 ;
Location in patent: Page/Page column 47-48 ;
反应条件
1.1: ethanol / 2 h / Reflux 2.1: 1,1'-carbonyldiimidazole / dichloromethane / 2 h / 20 °C 2.2: 20 °C View Scheme
反应条件
1.1: copper(ll) bromide / ethyl acetate / 1.5 h / Reflux 2.1: ethanol / 2 h / Reflux 3.1: 1,1'-carbonyldiimidazole / dichloromethane / 2 h / 20 °C 3.2: 20 °C View Scheme
