1: With borane-THF in tetrahydrofuran
3 h; Heating / reflux;
2: With methanol in tetrahydrofuran
T=20°C; 0.25 h; Heating / reflux;
3: With sodium hydroxide in water; ethyl acetate
参考文献
NOVO NORDISK A/S
Patent: WO2007/6814 A1, 2007 ;
Location in patent: Page/Page column 159-160 ;
WO 2007/006814 A1
