1-Boc-3-[(1,1-二甲基乙基) 二甲基甲硅烷基氧基甲基]-哌啶-4-酮合成路线 （共 5 条）
反应条件
oxalyl dichloride; dimethyl sulfoxide; triethylamine in dichloromethane Swern oxidation;
参考文献
SCHERING CORPORATION
Patent: US2005/182095 A1, 2005 ;
Location in patent: Page/Page column 19 ;
US 20050182095 A1
反应条件
1: 100 percent / Et3N / methanol; CH2Cl2 2: 92 percent / NaBH4 / methanol; tetrahydrofuran 3: 83 percent / Et3N; DMAP / CH2Cl2 4: 97 percent / (COCl)2; DMSO; Et3N / CH2Cl2 View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 5 p. 1375 - 1378
反应条件
1: 100 percent / Et3N / methanol; CH2Cl2 2: 92 percent / NaBH4 / methanol; tetrahydrofuran 3: 83 percent / Et3N; DMAP / CH2Cl2 4: 97 percent / (COCl)2; DMSO; Et3N / CH2Cl2 View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 5 p. 1375 - 1378
反应条件
1: 92 percent / NaBH4 / methanol; tetrahydrofuran 2: 83 percent / Et3N; DMAP / CH2Cl2 3: 97 percent / (COCl)2; DMSO; Et3N / CH2Cl2 View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 5 p. 1375 - 1378
反应条件
1: 83 percent / Et3N; DMAP / CH2Cl2 2: 97 percent / (COCl)2; DMSO; Et3N / CH2Cl2 View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 5 p. 1375 - 1378
