2-氯-5-甲氧基苯胺盐酸盐合成路线 (共 2 条)
反应条件
1: triethylamine / 1 h / 100 °C
2: Eaton's reagent / 90 - 100 °C / |Inert atmosphere
View Scheme
参考文献
Mistry, Shailesh N.; Valant, Celine; Sexton, Patrick M.; Capuano, Ben; Christopoulos, Arthur; Scammells, Peter J.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 12 p. 5151 - 5172
反应条件
sodium hydride in ethyl acetate; N,N-dimethyl-formamide
参考文献
GE HEALTHCARE LIMITED
Patent: US2011/70161 A1, 2011 ;