5-氯-2-三氟甲基苯甲酰氯合成路线 (共 3 条)
反应条件
thionyl chloride in toluene Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 49, # 12 p. 3659 - 3666
反应条件
1: NH4OH 2: 54 percent / trifluoroacetyl anhydride; NEt3 / CH2Cl2 View Scheme
参考文献
Nelson, Derek W.; Gregg, Robert J.; Kort, Michael E.; Perez-Medrano, Arturo; Voight, Eric A.; Wang, Ying; Grayson, George; Namovic, Marian T.; Donnelly-Roberts, Diana L.; Niforatos, Wende; Honore, Prisca; Jarvis, Michael F.; Faltynek, Connie R.; Carroll, William A.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 12 p. 3659 - 3666
参考文献
Carroll, William A.; Florjancic, Alan S.; Perez-Medrano, Arturo; Peddi, Sridhar
Patent: US2007/105842 A1, 2007 ;
Location in patent: Page/Page column 24 ;