diethylamine in tert-butyl methyl ether T=20 - 25°C; 1.5 h;

1.1: diethylamine / tert-butyl methyl ether 2.1: diethyl ether; tetrahydrofuran / 2 h / 10 - 15 °C 2.2: 5 °C 3.1: hydrogenchloride / water / 5 h / 55 °C 3.2: 20 °C / pH 12 4.1: hydrogenchloride; hydrogen / palladium 10 on activated carbon / ethanol; water / 20 °C / Inert atmosphere View Scheme

1.1: diethylamine / tert-butyl methyl ether 2.1: diethyl ether; tetrahydrofuran / 2 h / 10 - 15 °C 2.2: 5 °C 3.1: hydrogenchloride / water / 5 h / 55 °C 3.2: 20 °C / pH 12 4.1: hydrogenchloride; hydrogen / palladium 10 on activated carbon / ethanol; water / 20 °C / Inert atmosphere 5.1: methanesulfonic acid; dl-methionine / 72 h / 80 °C 5.2: pH 10 - 12 View Scheme