8-(3-二乙基氨基丙氧基)补骨脂素合成路线 （共 4 条）
反应条件
1.1: potassium phthalimide / N,N-dimethyl-acetamide / 20 °C
1.2: CH3NHNH2 / CHCl3 / 20 °C
2.1: ethanol / 65 °C
View Scheme
参考文献
Santana, Lourdes; Uriarte, Eugenio; Gonzalez-Diaz, Humberto; Zagotto, Giuseppe; Soto-Otero, Ramon; Mendez-Alvarez, Estefania
Journal of Medicinal Chemistry, 2006 , vol. 49, # 3 p. 1149 - 1156
反应条件
1.1: K2CO3 / acetone / Heating
2.1: potassium phthalimide / N,N-dimethyl-acetamide / 20 °C
2.2: CH3NHNH2 / CHCl3 / 20 °C
3.1: ethanol / 65 °C
View Scheme
参考文献
Santana, Lourdes; Uriarte, Eugenio; Gonzalez-Diaz, Humberto; Zagotto, Giuseppe; Soto-Otero, Ramon; Mendez-Alvarez, Estefania
Journal of Medicinal Chemistry, 2006 , vol. 49, # 3 p. 1149 - 1156
反应条件
1.1: AlCl3 / CH2Cl2 / 20 °C
2.1: K2CO3 / acetone / Heating
3.1: potassium phthalimide / N,N-dimethyl-acetamide / 20 °C
3.2: CH3NHNH2 / CHCl3 / 20 °C
4.1: ethanol / 65 °C
View Scheme
参考文献
Santana, Lourdes; Uriarte, Eugenio; Gonzalez-Diaz, Humberto; Zagotto, Giuseppe; Soto-Otero, Ramon; Mendez-Alvarez, Estefania
Journal of Medicinal Chemistry, 2006 , vol. 49, # 3 p. 1149 - 1156
参考文献
Santana, Lourdes; Uriarte, Eugenio; Gonzalez-Diaz, Humberto; Zagotto, Giuseppe; Soto-Otero, Ramon; Mendez-Alvarez, Estefania
Journal of Medicinal Chemistry, 2006 , vol. 49, # 3 p. 1149 - 1156
