3-(2-硝基苄基)-3H-咪唑-4-甲醛合成路线 (共 3 条)
反应条件
manganese(IV) oxide in 1,4-dioxane
17 h; Heating;
参考文献
Antonini, Ippolito; Cristalli, Gloria; Franchetti, Palmarisa; Grifantini, Mario; Martelli, Sante
Synthesis, 1983 , # 1 p. 47 - 49
反应条件
in acetonitrile
T=20 - 60°C; Inert atmosphere;
参考文献
Suryadevara, Praveen Kumar; Olepu, Srinivas; Lockman, Jeffrey W.; Ohkanda, Junko; Karimi, Mandana; Verlinde, Christophe L. M. J.; Kraus, James M.; Schoepe, Jan; Van Voorhis, Wesley C.; Hamilton, Andrew D.; Buckner, Frederick S.; Gelb, Michael H.
Journal of Medicinal Chemistry, 2009 , vol. 52, # 12 p. 3703 - 3715
反应条件
1: 30 percent / Na2CO3 / dimethylformamide / 7 h / 100 °C
2: 24 percent / activated MnO2 / dioxane / 17 h / Heating
View Scheme
参考文献
Antonini, Ippolito; Cristalli, Gloria; Franchetti, Palmarisa; Grifantini, Mario; Martelli, Sante
Synthesis, 1983 , # 1 p. 47 - 49