2-(2,3-二氧代-2,3-二氢-1H-吲哚-1-基)乙酰胺合成路线 （共 3 条）
反应条件
sodium hydride in N,N-dimethyl-formamide
T=0 - 20°C; 24 h; Inert atmosphere;
参考文献
Broeders, Fabienne; Defrere, Laurent; Deltent, Marie-France; Driessens, Frank; Gilson, Frederic; Grooters, Luc; Ikonomakos, Xavier; Limauge, Frederic; Sergeef, Emmanuel; Verstraeten, Natacha
Organic Process Research and Development, 2009 , vol. 13, # 3 p. 442 - 449
反应条件
1: indole-2,3-dione With polymeric BEMP in acetonitrile
T=25°C; deprotonation; 0.166667 h;
2: alpha-Bromoacetamide in acetonitrile
T=45°C; Alkylation; 16 h;
参考文献
Shuttleworth, Stephen J.; Nasturica, Daniel; Gervais, Christian; Siddiqui, M. Arshad; Rando, Robert F.; Lee, Nola
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 22 p. 2501 - 2504
参考文献
Langenbeck
Chemische Berichte, 1928 , vol. 61, p. 944
