5-(4-(三氟甲氧基)苯基)吡啶甲酸合成路线 (共 1 条)
反应条件
1: With sodium carbonate; bis-triphenylphosphine-palladium(II) chloride in ethylene glycol dimethyl ether; water
T=90°C;
2: With water in ethylene glycol dimethyl ether
3: With hydrogenchloride; water in ethylene glycol dimethyl ether; ethyl acetate
pH=2;
参考文献
BAYER HEALTHCARE AG
Patent: WO2005/40100 A1, 2005 ;
Location in patent: Page/Page column 106-107 ;
WO 2005/040100 A1