6-(4-(三氟甲氧基)苯基)烟酸合成路线 (共 2 条)
反应条件
1: With ethylene glycol dimethyl ether; sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in ethylene glycol dimethyl ether; water
T=80°C; 16 h;
2: With water in ethylene glycol dimethyl ether
参考文献
BAYER HEALTHCARE AG
Patent: WO2005/40100 A1, 2005 ;
Location in patent: Page/Page column 107-108 ;
WO 2005/040100 A1
反应条件
1: With potassium hydroxide in methanol; water
T=40°C;
2: With hydrogenchloride; water
pH=2;
3: With diethyl ether
参考文献
BAYER HEALTHCARE AG
Patent: WO2005/40100 A1, 2005 ;
Location in patent: Page/Page column 108-109 ;
WO 2005/040100 A1