(R)-2-((4-(三氟甲基)苯氧基)甲基)环氧乙烷合成路线 （共 3 条）
反应条件
1: 4-(trifluoromethyl)phenol With potassium carbonate in butanone
T=20°C; 0.166667 h; Inert atmosphereSchlenk technique;
2: (R)-(-)-epichlorohydrin in butanone
T=90°C; 15 h; Inert atmosphereSchlenk technique;
参考文献
Park, Jung-Eun; Ji, Wan Keun; Jang, Jae Wan; Pae, Ae Nim; Choi, Keehyun; Choi, Ki Hang; Kang, Jahyo; Roh, Eun Joo
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 6 p. 1887 - 1890
反应条件
caesium carbonate in acetonitrile
Reflux;
参考文献
Sun, Dianqing; Scherman, Michael S.; Jones, Victoria; Hurdle, Julian G.; Woolhiser, Lisa K.; Knudson, Susan E.; Lenaerts, Anne J.; Slayden, Richard A.; McNeil, Michael R.; Lee, Richard E.
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 10 p. 3588 - 3594
参考文献
Zhang, Rui; Wang, Aihua; DeAngelis, Alan; Pelton, Patricia; Xu, Jun; Zhu, Peifang; Zhou, Lubing; Demarest, Keith; Murray, William V.; Kuo, Gee-Hong
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 14 p. 3855 - 3859
