正丁基硼酸(1S,2S,3R,5S)-(+)-2,3-蒎烷二醇酯合成路线 （共 4 条）
反应条件
in diethyl ether T=20°C; 3 h;
参考文献
Shreder, Kevin R.; Wong, Melissa S.; Corral, Sergio; Yu, Zhizhou; Winn, David T.; Wu, Min; Hu, Yi; Nomanbhoy, Tyzoon; Alemayehu, Senaiet; Fuller, Stacy R.; Rosenblum, Jonathan S.; Kozarich, John W.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 19 p. 4256 - 4260
参考文献
Matteson,D.S.; Sadhu,K.M.; Peterson,M.L.
Journal of the American Chemical Society, 1986 , vol. 108, p. 810
反应条件
1: (s)-pinanediol butylboronate With sec.-butyllithium in tetrahydrofuran; cyclohexane T=-78 - 20°C; Suzuki-Miyaura reaction; 1.5 h; 2: 4-bromo-N,N-dimethyl-aniline With sodium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in tetrahydrofuran T=70 - 80°C;
参考文献
Zou, Gang; Falck
Tetrahedron Letters, 2001 , vol. 42, # 34 p. 5817 - 5819
反应条件
hydroxide; dihydrogen peroxide; LiN(Cy)2
1.) THF, -78 deg C, 10 min, 2.) THF, from 0 deg C to 50 deg C; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Kabalka, George W.; Li, Nan-Sheng; Yu, Su
Tetrahedron Asymmetry, 1997 , vol. 8, # 23 p. 3843 - 3846
