甲基2-乙酰氨基-3,6-二-O-苄基-2-脱氧吡喃己糖苷合成路线 （共 7 条）
反应条件
hydrogenchloride; sodium cyanoborohydride in tetrahydrofuran; diethyl ether
T=0°C; 1 h;
参考文献
Crich; Dudkin
Journal of the American Chemical Society, 2001 , vol. 123, # 28 p. 6819 - 6825
反应条件
triethylsilane; boron trifluoride diethyl etherate in dichloromethane
T=0°C;
参考文献
Petersen; Jensen
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 18 p. 2175 - 2182
反应条件
hydrogenchloride; 3 A molecular sieve; sodium cyanoborohydride in tetrahydrofuran; diethyl ether
T=0°C; 3 h;
参考文献
Rana, Surjit S.; Barlow, Joseph J.; Matta, Khushi L.
Carbohydrate Research, 1983 , vol. 113, p. 257 - 272
反应条件
1: NaH / tetrahydrofuran
2: 220 mg / i-Pr2NEt / CH2Cl2 / 12 h
3: 50 percent / NaBH3CN; 1M HCl / diethyl ether; tetrahydrofuran / 1 h / 0 °C
View Scheme
参考文献
Crich; Dudkin
Journal of the American Chemical Society, 2001 , vol. 123, # 28 p. 6819 - 6825
反应条件
1: NaH / tetrahydrofuran
2: 220 mg / i-Pr2NEt / CH2Cl2 / 12 h
3: 50 percent / NaBH3CN; 1M HCl / diethyl ether; tetrahydrofuran / 1 h / 0 °C
View Scheme
参考文献
Crich; Dudkin
Journal of the American Chemical Society, 2001 , vol. 123, # 28 p. 6819 - 6825
反应条件
1: 53 percent / potassium hydroxide / dimethylformamide / 2.25 h / 70 - 75 °C
2: 81.2 percent / sodium cyanoborohydride, 3A molecular sieves, hydrogen chloride / diethyl ether; tetrahydrofuran / 3 h / 0 °C
View Scheme
参考文献
Rana, Surjit S.; Barlow, Joseph J.; Matta, Khushi L.
Carbohydrate Research, 1983 , vol. 113, p. 257 - 272
反应条件
1: 53 percent / potassium hydroxide / dimethylformamide / 2.25 h / 70 - 75 °C
2: 81.2 percent / sodium cyanoborohydride, 3A molecular sieves, hydrogen chloride / diethyl ether; tetrahydrofuran / 3 h / 0 °C
View Scheme
参考文献
Rana, Surjit S.; Barlow, Joseph J.; Matta, Khushi L.
Carbohydrate Research, 1983 , vol. 113, p. 257 - 272
