6-甲基-4-苯基-1,2,3,5-四氢二环戊二烯并苯合成路线 （共 4 条）
反应条件
toluene-4-sulfonic acid in toluene
3 h; Heating / reflux;
参考文献
DOW GLOBAL TECHNOLOGIES INC.
Patent: WO2004/13149 A1, 2004 ;
Location in patent: Page/Page column 14 ;
反应条件
1.1: triphenylphosphine-3,3',3''-trisulfonic acid trisodium salt; palladium diacetate; sodium carbonate / water; ethylene glycol / 3 h / 80 °C / Inert atmosphere; Reflux
2.1: methanol; sodium tetrahydroborate / toluene / 3 h / 50 °C / Inert atmosphere
2.2: 0.5 h / Inert atmosphere
3.1: toluene-4-sulfonic acid / toluene / 1 h / Reflux; Inert atmosphere
View Scheme
参考文献
Nifant'ev, Ilya E.; Ivchenko, Pavel V.; Bagrov, Vladimir V.; Okumura, Yoshikuni; Elder, Michael; Churakov, Andrei V.
Organometallics, 2011 , vol. 30, # 21 p. 5744 - 5752
反应条件
1.1: AlCl3, aluminium chloride / dichloromethane / 17.5 h / 0 - 20 °C / Inert atmosphere
1.2: Inert atmosphere; Cooling with ice
2.1: AlCl3, aluminium chloride; bromine / chloroform / 0 °C / Inert atmosphere
2.2: 0 °C / Inert atmosphere
3.1: triphenylphosphine-3,3',3''-trisulfonic acid trisodium salt; palladium diacetate; sodium carbonate / water; ethylene glycol / 3 h / 80 °C / Inert atmosphere; Reflux
4.1: methanol; sodium tetrahydroborate / toluene / 3 h / 50 °C / Inert atmosphere
4.2: 0.5 h / Inert atmosphere
5.1: toluene-4-sulfonic acid / toluene / 1 h / Reflux; Inert atmosphere
View Scheme
参考文献
Nifant'ev, Ilya E.; Ivchenko, Pavel V.; Bagrov, Vladimir V.; Okumura, Yoshikuni; Elder, Michael; Churakov, Andrei V.
Organometallics, 2011 , vol. 30, # 21 p. 5744 - 5752
反应条件
1.1: triphenylphosphine-3,3',3''-trisulfonic acid trisodium salt; palladium diacetate; sodium carbonate / water; ethylene glycol / 3 h / 80 °C / Inert atmosphere; Reflux
2.1: methanol; sodium tetrahydroborate / toluene / 3 h / 50 °C / Inert atmosphere
2.2: 0.5 h / Inert atmosphere
3.1: toluene-4-sulfonic acid / toluene / 1 h / Reflux; Inert atmosphere
View Scheme
参考文献
Nifant'ev, Ilya E.; Ivchenko, Pavel V.; Bagrov, Vladimir V.; Okumura, Yoshikuni; Elder, Michael; Churakov, Andrei V.
Organometallics, 2011 , vol. 30, # 21 p. 5744 - 5752
