1: 1.) Pd2(dba)3*CHCl3, dppe / 2.) THF, 50 deg C, 3 h 2: 10percent aq. NaOH / methanol / Ambient temperature 3: benzene / 1 h / Heating View Scheme

tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran 5 h; Heating; Yield given. Yields of byproduct given;

sodium hydroxide; oxonium; 1,2-bis-(diphenylphosphino)ethane; tris(dibenzylideneacetone)dipalladium(0) chloroform complex 1.) THF, 50 deg C, 3 h; Yield given. Multistep reaction;

tris(dibenzylideneacetone)dipalladium(0) chloroform complex; formic acid; N,N,N',N'-tetra-methylnaphthalene-1,8-diamine; (R)-(+)-3-diphenylphosphino-3'-methoxy-4,4'-biphenanthryl in 1,4-dioxane T=20°C; 15 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

formic acid; triethylamine; tris(dibenzylideneacetone)dipalladium(0) chloroform complex; tributylphosphine in tetrahydrofuran 2 h; Heating;

tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran 5 h; Heating; Yield given. Yields of byproduct given;

sodium azide; polystyrene-PEG resin-bound triarylphosphine-Pd complex in water T=25°C; 24 h;