1-Boc-4-(4-氨甲基苯基)哌嗪合成路线 （共 4 条）
反应条件
lithium hydroxide; hydrogen; palladium on activated charcoal; nickel in ethyl acetate
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 10 p. 2584 - 2589
反应条件
1: 89 percent / K2CO3 / dimethylsulfoxide / 8 h / 90 °C 2: H2; LiOH / Raney-Ni; Pd/C / ethyl acetate View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 10 p. 2584 - 2589
反应条件
1: 89 percent / K2CO3 / dimethylsulfoxide / 8 h / 90 °C 2: H2; LiOH / Raney-Ni; Pd/C / ethyl acetate View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 10 p. 2584 - 2589
反应条件
1: Et3N / CH2Cl2 / 6 h / 20 °C
2: aq. HCl / tetrahydrofuran / 1 h / 0 - 20 °C
View Scheme
参考文献
Tangallapally, Rajendra P.; Lee, Robin E.B.; Lenaerts, Anne J.M.; Lee, Richard E.
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 10 p. 2584 - 2589
