4-乙氧基-2,6-吡啶二甲酸合成路线 （共 5 条）
反应条件
1: 57 percent / C6H5POCl2 / 3 h / 130 °C
View Scheme
参考文献
Chaubet; Nguyen Van Duong; Courtieu; Gaudemer; Gref; Crumbliss
Canadian Journal of Chemistry, 1991 , vol. 69, # 7 p. 1107 - 1116
反应条件
1: 52 percent / CH2Cl2 / 2 h / Heating
2: 1) NaH, 2) crown ether (18-c-6) / 1) THF, room temp., 1 h, 2) THF, reflux, 1 h
3: 1) KOH, 2) HCl
View Scheme
参考文献
Chaubet; Nguyen Van Duong; Courtieu; Gaudemer; Gref; Crumbliss
Canadian Journal of Chemistry, 1991 , vol. 69, # 7 p. 1107 - 1116
反应条件
potassium hydroxide; 15-crown-5
1) ethanol; Yield given. Multistep reaction;
参考文献
Chaubet, Frederic; Nguyen Van Duong, Marguerite; Gref, Aurore; Courtieu, Jacques; Crumbliss, Alvin L.; Gaudemer, Alain
Tetrahedron Letters, 1990 , vol. 31, # 40 p. 5729 - 5732
反应条件
1: 1) NaH, 2) crown ether (18-c-6) / 1) THF, room temp., 1 h, 2) THF, reflux, 1 h
2: 1) KOH, 2) HCl
View Scheme
参考文献
Chaubet; Nguyen Van Duong; Courtieu; Gaudemer; Gref; Crumbliss
Canadian Journal of Chemistry, 1991 , vol. 69, # 7 p. 1107 - 1116
反应条件
Yield given. Multistep reaction;
参考文献
Chaubet; Nguyen Van Duong; Courtieu; Gaudemer; Gref; Crumbliss
Canadian Journal of Chemistry, 1991 , vol. 69, # 7 p. 1107 - 1116
