1: With boron tribromide in chloroform Reflux; 2: With water; sodium hydroxide in chloroform pH=>= 12; 3: With hydrogenchloride in water; ethyl acetate pH=5.5 - 6.5;

1.1: hydrogen; potassium hydroxide / palladium/alumina / ethanol / 375.04 Torr 2.1: 1H-imidazole / N,N-dimethyl-formamide 3.1: magnesium / tetrahydrofuran; ethylene dibromide / 0.75 h / 35 °C 4.1: hydrogen / palladium/alumina / tetrahydrofuran 5.1: water; potassium fluoride / tetrahydrofuran / Reflux 6.1: boron tribromide / chloroform / Reflux 6.2: pH >= 12 6.3: pH 5.5 - 6.5 View Scheme

1.1: 1H-imidazole / N,N-dimethyl-formamide 2.1: magnesium / tetrahydrofuran; ethylene dibromide / 0.75 h / 35 °C 3.1: hydrogen / palladium/alumina / tetrahydrofuran 4.1: water; potassium fluoride / tetrahydrofuran / Reflux 5.1: boron tribromide / chloroform / Reflux 5.2: pH >= 12 5.3: pH 5.5 - 6.5 View Scheme

1.1: hydrogen / palladium/alumina / tetrahydrofuran 2.1: water; potassium fluoride / tetrahydrofuran / Reflux 3.1: boron tribromide / chloroform / Reflux 3.2: pH >= 12 3.3: pH 5.5 - 6.5 View Scheme

1.1: magnesium / tetrahydrofuran; ethylene dibromide / 0.75 h / 35 °C 2.1: hydrogen / palladium/alumina / tetrahydrofuran 3.1: water; potassium fluoride / tetrahydrofuran / Reflux 4.1: boron tribromide / chloroform / Reflux 4.2: pH >= 12 4.3: pH 5.5 - 6.5 View Scheme

1.1: water; potassium fluoride / tetrahydrofuran / Reflux 2.1: boron tribromide / chloroform / Reflux 2.2: pH >= 12 2.3: pH 5.5 - 6.5 View Scheme