alpha-溴-2-氯苯乙酸甲酯合成路线 （共 22 条）
反应条件
1: 4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride With sodium carbonate in water
1 h; Heating / reflux;
2: 2-chloro-α-methoxycarbonylbenzyl bromide in water; 1,2-dichloro-ethane
T=25°C; 8 h; Product distribution / selectivity;
参考文献
IPCA Laboratories Limited
Patent: EP1772455 A2, 2007 ;
Location in patent: Page/Page column 10 ;
反应条件
potassium carbonate in methanol; ethyl acetate
4 h; Heating / reflux; Product distribution / selectivity;
参考文献
BATTULA, Srinivasa Reddy
Patent: EP1980563 A1, 2008 ;
Location in patent: Page/Page column 10 ;
