3,5-二甲基吡唑-1-甲醇合成路线 （共 6 条）
参考文献
Lee, Hyosun; Kim, Eunhee; Woo, Hyun Yul; Kim, Sunghoon; Lee, Hajin; Kim, Dongil
Polyhedron, 2012 , vol. 42, # 1 p. 135 - 141
反应条件
1: hydrazine hydrate / ethanol 2: ethanol / 12 h / 20 °C View Scheme
参考文献
Medicinal Chemistry Research, , vol. 21, # 10 p. 2772 - 2778,7
反应条件
potassium hydroxide 1.) MeOH, 0.5 h, 2.) MeOH, MeCN, 72 h; Yield given. Multistep reaction;
参考文献
Heterocycles, , vol. 34, # 6 p. 1227 - 1230
反应条件
bromine; sodium acetate
参考文献
Dvoretzky; Richter
Journal of Organic Chemistry, 1950 , vol. 15, p. 1285,1287
反应条件
1: 98 percent / thionyl chloride / CHCl3 / 3 h / Ambient temperature
2: 85 percent / potassium hydroxide, potassium carbonate, tetrabutylammonium hydrogensulfate / benzene / 1.) reflux, 8 h, 2.) RT, 16 h
View Scheme
参考文献
Julia, Sebastian; Martinez-Martorell, Carlos; Elguero, Jose
Heterocycles, 1986 , vol. 24, # 8 p. 2233 - 2237
