1,3-二甲基-1H-吡唑-4-羧酸乙酯合成路线 （共 23 条）
反应条件
1: 70 percent / NaOEt / ethanol / 4 h / 80 °C 2: 70 percent / ethanol / 80 °C 3: ethanol / 24 h / 80 °C View Scheme
参考文献
Synlett, , # 4 p. 703 - 707
反应条件
1: 83 percent / hydrazine hydrate / ethanol / -10 - 20 °C 2: sodium ethoxide / ethanol / 2 h / Heating View Scheme
参考文献
Australian Journal of Chemistry, , vol. 36, # 1 p. 135 - 147
反应条件
hydrogenchloride; sodium nitrite; sulfur dioxide 1) < 10 deg C, 10 min, 2) CCl4, room temp., 1 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Journal of Heterocyclic Chemistry, , vol. 28, # 6 p. 1545 - 1547
反应条件
in ethanol T=80°C; 24 h; Title compound not separated from byproducts;
参考文献
Synlett, , # 4 p. 703 - 707
反应条件
in ethanol T=20°C; 24 h; Title compound not separated from byproducts;
参考文献
Synlett, , # 4 p. 703 - 707
反应条件
in ethanol T=80°C; 24 h; Title compound not separated from byproducts;
参考文献
Synlett, , # 4 p. 703 - 707
反应条件
sodium ethanolate in ethanol 2 h; Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Australian Journal of Chemistry, , vol. 36, # 1 p. 135 - 147
反应条件
1: 70 percent / ethanol / 80 °C 2: ethanol / 24 h / 80 °C View Scheme
参考文献
Synlett, , # 4 p. 703 - 707
反应条件
sulfuric acid; copper; acetic acid; sodium nitrite 1.) from 0 deg C to 5 deg C, 30 min, 2.) from 0 deg C to RT, 30 min; Yield given. Multistep reaction;
参考文献
Australian Journal of Chemistry, , vol. 36, # 1 p. 135 - 147
反应条件
in methanol 1) 0 deg C, 15 min.; 2) room temp., 1 h; Yield given. Yields of byproduct given;
参考文献
Journal of Heterocyclic Chemistry, , vol. 24, # 6 p. 1669 - 1675
