(2-氨基-6-氧代-1,6-二氢-嘧啶-5-基)-乙酸合成路线 （共 4 条）
反应条件
sodium methylate in methanol; water
参考文献
ISIS Pharmaceuticals, Inc.; PepSeptive Biosystems, Inc.
Patent: US6441130 B1, 2002 ;
反应条件
sodium hydroxide in water
2 h; Ambient temperature; Yield given;
参考文献
Beran; Cerny; Krepelka; Vachek
Collection of Czechoslovak Chemical Communications, 1983 , vol. 48, # 1 p. 292 - 298
反应条件
1: Na / methanol / 3 h / Heating
2: NaOH / H2O / 2 h / Ambient temperature
View Scheme
参考文献
Beran; Cerny; Krepelka; Vachek
Collection of Czechoslovak Chemical Communications, 1983 , vol. 48, # 1 p. 292 - 298
反应条件
1: formic acid methyl ester; succinic acid dimethyl ester
2: 1-methylguanidine hydrochloride
参考文献
Wojciechowski, Filip; Hudson, Robert H. E.
Canadian Journal of Chemistry, 2008 , vol. 86, # 11 p. 1026 - 1029
