(R)-n-甲氧基-n-甲基-1-((s)-1-苯基乙基)氮丙啶-2-羧酰胺合成路线 （共 4 条）
反应条件
isopropylmagnesium chloride in tetrahydrofuran
T=0 - 20°C;
参考文献
Kim, Jin-Wook; Kim, Yong-Woo; Inagaki, Yuichi; Hwang, You-A; Mitsutake, Susumu; Ryu, Yeon-Woo; Lee, Won Koo; Ha, Hyun-Joon; Park, Chang-Seo; Igarashi, Yasuyuki
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 10 p. 3475 - 3485
反应条件
iso-propylmagnesium bromide in tetrahydrofuran
T=0 - 20°C; 0.166667 h;
参考文献
DOOSAN CORPORATION; IMAGENE CO., LTD.
Patent: WO2006/4359 A1, 2006 ;
Location in patent: Page/Page column 11; 12; 15; 16; 18; 20; 22 ;
WO 2006/004359 A1
反应条件
iso-propylmagnesium bromide in tetrahydrofuran
T=0°C;
参考文献
Ha, Hyun-Joon; Hong, Myeng Chan; Ko, Seung Whan; Kim, Yong Woo; Lee, Won Koo; Park, Jungchan
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 7 p. 1880 - 1883
反应条件
iso-propylmagnesium bromide in tetrahydrofuran
T=0°C; Inert atmosphere;
参考文献
Singh, Alok; Ha, Hyun-Joon; Park, Jungchan; Kim, Jun Hee; Lee, Won Koo
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 21 p. 6174 - 6181
