3-氨基-1H-吡咯-2,4-二甲酸2,4-二乙酯合成路线 （共 4 条）
反应条件
1: With sodium ethanolate in ethanol T=20°C; 20 h; Heating / reflux; 2: With acetic acid in ethanol
参考文献
Bender, John A.; Yang, Zhong; Kadow, John F.; Meanwell, Nicholas A.
Patent: US2005/124623 A1, 2005 ;
Location in patent: Page/Page column 43 ;
反应条件
sodium ethanolate in ethanol 14 h; Reflux;
参考文献
ARRAY BIOPHARMA INC.; GENENTECH, INC.; ALIAGAS, Ignacio; GRADL, Stefan; GUNZNER, Janet; MATHIEU, Simon; PULK, Rebecca; RUDOLPH, Joachim; WEN, Zhaoyang; GRINA, Jonas; HANSEN, Joshua D.; LAIRD, Ellen; MORENO, David; REN, Li; WENGLOWSKY, Steven Mark
Patent: WO2011/25940 A1, 2011 ;
Location in patent: Page/Page column 85 ;
WO 2011/025940 A1
反应条件
sodium methylate in methanol
参考文献
US6693193 B1, ;
Page column 14 ;
反应条件
1: in ethanol Reflux; 2: With trichlorophosphate Reflux; 3: With sodium hydrogencarbonate 2 h;
参考文献
WO2011/25940 A1, ;
Page/Page column 85 ;
WO 2011/025940 A1
