1: dihydrogen peroxide; sodium hydroxide / tetrahydrofuran; water / 4 h / 20 °C 2: pyridine / 16 h / 0 - 20 °C / Inert atmosphere 3: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / N,N-dimethyl-formamide / 16 h / 80 °C / Inert atmosphere View Scheme

1: dihydrogen peroxide; sodium hydroxide / tetrahydrofuran; water / 4 h / 20 °C 2: pyridine / 16 h / 0 - 20 °C / Inert atmosphere 3: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / N,N-dimethyl-formamide / 16 h / 80 °C / Inert atmosphere 4: sodium carbonate / methanol; water / 16 h / 20 °C View Scheme

dihydrogen peroxide; sodium hydroxide in tetrahydrofuran; water T=20°C; 4 h;