4-氯-7-(4-甲氧基苄基)-6,7-二氢-5H-吡咯并[2,3-d]嘧啶合成路线 （共 3 条）
反应条件
triethylamine in 1,2-dichloro-ethane Heating / reflux;
参考文献
ARRAY BIOPHARMA INC.
Patent: WO2005/51304 A2, 2005 ;
Location in patent: Page/Page column 155-157 ;
WO 2005/051304 A2
反应条件
1: N-ethyl-N,N-diisopropylamine / ethanol / 5 h / |Reflux 2: sulfuryl dichloride / toluene / 1 h / |Reflux 3: potassium carbonate / N,N-dimethyl-formamide / 2 h / 110 °C View Scheme
反应条件
1: N-ethyl-N,N-diisopropylamine / ethanol / 5 h / |Reflux 2: sulfuryl dichloride / toluene / 1 h / |Reflux 3: potassium carbonate / N,N-dimethyl-formamide / 2 h / 110 °C View Scheme
