sodium chlorate; osmium(VIII) oxide in methanol; water Ambient temperatureovernight;

1: 89 percent / aq. NaOH 2: 62 percent / aq. ClCH2CO2H / 4 h / Heating 3: 17.3 percent / OsO4, NaClO3 / H2O; methanol / 24 h / Ambient temperature View Scheme

1: 14.2 g / Na/CH3OH / 10 h / Heating 2: 89 percent 3: 62 percent / chloroacetic acid / H2O / 4 h / Heating 4: 17 percent / OsO4, NaClO3 / H2O; methanol / Ambient temperature; overnight View Scheme

1: 62 percent / aq. ClCH2CO2H / 4 h / Heating 2: 17.3 percent / OsO4, NaClO3 / H2O; methanol / 24 h / Ambient temperature View Scheme

1: 64 percent / MeONa / methanol / 10 h / Heating 2: 89 percent / aq. NaOH 3: 62 percent / aq. ClCH2CO2H / 4 h / Heating 4: 17.3 percent / OsO4, NaClO3 / H2O; methanol / 24 h / Ambient temperature View Scheme