1: With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.666667 h; 2: With boric acid trimethyl ester in tetrahydrofuran; hexane T=-78 - 20°C; 18 h; 3: With hydrogenchloride in tetrahydrofuran; hexane; water

in phosphate buffer pH=6.9 - 7.0; Kinetics;