5-(2-氯苯基)-3-吡啶羧醛合成路线 （共 3 条）
反应条件
diisobutylaluminium hydride in dichloromethane
T=-78°C; 3 h;
参考文献
Pfefferkorn, Jeffrey A.; Greene, Meredith L.; Nugent, Richard A.; Gross, Rebecca J.; Mitchell, Mark A.; Finzel, Barry C.; Harris, Melissa S.; Wells, Peter A.; Shelly, John A.; Anstadt, Robert A.; Kilkuskie, Robert E.; Kopta, Laurice A.; Schwende, Francis J.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 10 p. 2481 - 2486
反应条件
1: Pd(Ph3P)4; Na2CO3 / 12 h / 80 °C
2: DIBAL / CH2Cl2 / 3 h / -78 °C
View Scheme
参考文献
Pfefferkorn, Jeffrey A.; Greene, Meredith L.; Nugent, Richard A.; Gross, Rebecca J.; Mitchell, Mark A.; Finzel, Barry C.; Harris, Melissa S.; Wells, Peter A.; Shelly, John A.; Anstadt, Robert A.; Kilkuskie, Robert E.; Kopta, Laurice A.; Schwende, Francis J.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 10 p. 2481 - 2486
反应条件
1: Pd(Ph3P)4; Na2CO3 / 12 h / 80 °C
2: DIBAL / CH2Cl2 / 3 h / -78 °C
View Scheme
参考文献
Pfefferkorn, Jeffrey A.; Greene, Meredith L.; Nugent, Richard A.; Gross, Rebecca J.; Mitchell, Mark A.; Finzel, Barry C.; Harris, Melissa S.; Wells, Peter A.; Shelly, John A.; Anstadt, Robert A.; Kilkuskie, Robert E.; Kopta, Laurice A.; Schwende, Francis J.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 10 p. 2481 - 2486
