3-氨基-3-甲基丁酸乙酯合成路线 （共 7 条）
反应条件
in dichloromethane 18 h;
参考文献
Thaisrivongs; Pals; DuCharme; Turner; DeGraaf; Lawson; Couch; Williams
Journal of Medicinal Chemistry, 1991 , vol. 34, # 2 p. 633 - 642
反应条件
1: 81 percent / CH2Cl2 / 18 h 2: 82 percent / aq. KOH / tetrahydrofuran / 18 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 34, # 2 p. 633 - 642
反应条件
triethylamine in dichloromethane
参考文献
Merrell Dow Pharmaceuticals Inc.
Patent: US4696927 A1, 1987 ;
US 4696927 A
反应条件
ammonia in ethanol
T=80°C; 22 h;
参考文献
Thaisrivongs; Pals; DuCharme; Turner; DeGraaf; Lawson; Couch; Williams
Journal of Medicinal Chemistry, 1991 , vol. 34, # 2 p. 633 - 642
反应条件
sodium ethanolate
anschliessend mit wss.HCl;
参考文献
Graf,R.
Justus Liebigs Annalen der Chemie, 1963 , vol. 661, p. 111 - 157
Full Text Show Details
Farbw.Hoechst
Patent: DE955509 , 1956 ;
反应条件
(i), (ii) HCl; Multistep reaction;
参考文献
Graf,R.
Justus Liebigs Annalen der Chemie, 1963 , vol. 661, p. 111 - 157
参考文献
Philippi; Galter
Monatshefte fuer Chemie, 1929 , vol. 51, p. 264
