2-溴-3,5-二甲氧基苯甲醛合成路线 （共 13 条）
反应条件
n-butyllithium; nitrobenzene
1.) THF, hexane, -75 deg C, 50 min.; 2.) -75 deg C, 4h, -> room temp.; Yield given. Multistep reaction;
参考文献
Sinhababu, Achintya K.; Borchardt, Ronald T.
Journal of Organic Chemistry, 1983 , vol. 48, # 12 p. 1941 - 1944
反应条件
Yield given. Multistep reaction;
参考文献
Sinhababu, Achintya K.; Borchardt, Ronald T.
Journal of Organic Chemistry, 1983 , vol. 48, # 14 p. 2356 - 2360
反应条件
1: 2.) SOCl2 / 1) THF, 0 deg C, 30 min; 2) THF, 1 h
2: 1.) n-BuLi / 1) THF, hexane, -78 deg C, 1 h; 2) THF, hexane, -78 deg C --> rt
3: SnCl4 / toluene / 0.33 h / 0 °C
4: 95 percent / H2 / Pd/C / ethyl acetate / 72 h
View Scheme
参考文献
Broering, Teresa J.; Morrow, Gary W.
Synthetic Communications, 1999 , vol. 29, # 7 p. 1135 - 1142
