(R )-(+),-4,4,4-三氟-3-羟基丁酸乙酯合成路线 （共 11 条）
反应条件
Daucas carota root; extract of in water T=37 - 40°C; pH=6.5; 56 h; Enzymatic reactionAqueous phosphate buffer; Conversion of starting material;
参考文献
Council of Scientific and Industrial Research
Patent: US7056540 B2, 2006 ;
Location in patent: Page/Page column 6; 9 ;
反应条件
D-glucose; D-glucose dehydrogenase; Pichia guilliermondii; nicotinamide adenine dinucleotide phosphate; sodium hydroxide in aq. phosphate buffer; dimethyl sulfoxide T=20°C; pH=6.5; 6 h; Enzymatic reaction;
参考文献
Xu, Guochao; Yu, Huilei; Xu, Jianhe
Chinese Journal of Chemistry, 2013 , vol. 31, # 3 p. 349 - 354
反应条件
chloro-trimethyl-silane T=20°C; Esterification; 48 h;
参考文献
Goetzoe, Stephan P.; Seebach, Dieter; Sanglier, Jean-Jacques
European Journal of Organic Chemistry, 1999 , # 10 p. 2533 - 2544
反应条件
sodium hydroxide in acetone 12 h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 52, # 15 p. 3211 - 3217
反应条件
magnesium chloride; Candida rugosa lipase in di-isopropyl ether; water T=30°C; 24 h;
参考文献
Tetrahedron, , vol. 61, # 8 p. 2169 - 2186
反应条件
Fala baker' yeast; allyl alcohol Microbiological reaction;
参考文献
Bertau, Martin
Tetrahedron Letters, 2001 , vol. 42, # 7 p. 1267 - 1268
反应条件
disodium hydrogenphosphate; potassium dihydrogenphosphate T=40 - 41°C; 6 h; asymmetric hydrolysis, cellulase (Trichoderma viride);
参考文献
Journal of Fluorine Chemistry, , vol. 34, p. 461 - 470
参考文献
Chemische Berichte, , vol. 125, # 12 p. 2795 - 2802
反应条件
Fala baker' yeast; allyl alcohol
参考文献
Tetrahedron Letters, , vol. 42, # 7 p. 1267 - 1268
反应条件
lithium aluminium tetrahydride
参考文献
Yamazaki, Takashi; Okamura, Naoko; Kitazume, Tomoya
Tetrahedron: Asymmetry, 1990 , vol. 1, # 8 p. 521 - 524
