(3S)-boc-3-氨基-4-苯基-2-丁酮合成路线 （共 18 条）
反应条件
1: With ozone in methanol; dichloromethane T=-78°C; 2: With dimethylsulfide in methanol; dichloromethane T=-78 - 20°C;
参考文献
Xiao, Jingbo; Weisblum, Bernard; Wipf, Peter
Organic Letters, 2006 , vol. 8, # 21 p. 4731 - 4734
反应条件
in ethylene glycol dimethyl ether; diethyl ether T=0 - 5°C; 6 h;
参考文献
Kawai, Megumi; Boparai, Amrit S.; Bernatowicz, Michael S.; Rich, Daniel H.
Journal of Organic Chemistry, 1983 , vol. 48, # 11 p. 1876 - 1879
反应条件
in tetrahydrofuran; diethyl ether T=0 - 20°C; Inert atmosphere;
参考文献
Pradhan, Tarun K.; Krishnan, K. Syam; Vasse, Jean-Luc; Szymoniak, Jan
Organic Letters, 2011 , vol. 13, # 7 p. 1793 - 1795
反应条件
hydrogen; palladium on activated charcoal in methanol T=20°C; 1 h;
参考文献
Tetrahedron Letters, , vol. 42, # 36 p. 6337 - 6340
反应条件
in tetrahydrofuran T=-78°C;
参考文献
Ohba, Tsuyoshi; Ikeda, Eitatsu; Takei, Hisashi
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 16 p. 1875 - 1880
反应条件
in tetrahydrofuran T=-30°C; 1.5 h;
参考文献
Radunz, Hans-Eckart; Reissig, Hans-Ulrich; Schneider, Guenther; Riethmueller, Angelika
Liebigs Annalen der Chemie, 1990 , # 7 p. 705 - 707
反应条件
in tetrahydrofuran T=-78°C;
参考文献
Godfrey, Lollie D.; Gordon, Eric M.; Langen, Derek J. Von
Tetrahedron Letters, 1987 , vol. 28, # 15 p. 1603 - 1606
反应条件
1: 67 percent / LDA / pentane; ethylbenzene; tetrahydrofuran / 1 h / -78 °C 2: 4 percent Chromat. / H2 / Pd/C / methanol / 1 h / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 42, # 36 p. 6337 - 6340
反应条件
1.1: benzotriazol-1-ol; dicyclohexyl-carbodiimide / dichloromethane / 0.17 h / Inert atmosphere 1.2: 12 h / Inert atmosphere 2.1: tetrahydrofuran; diethyl ether / 0 - 20 °C / Inert atmosphere View Scheme
参考文献
Organic Letters, , vol. 13, # 7 p. 1793 - 1795
反应条件
hydrogen; triethylamine; Pd-BaSO4 in methanol 2.5 h;
参考文献
Tetrahedron Letters, , vol. 42, # 36 p. 6337 - 6340
