2-(叔丁氧基羰基氨基)-4-甲氧基-4-氧代丁酸合成路线 (共 3 条)
反应条件
1: With sodium carbonate in 1,4-dioxane; water 2: With di-tert-butyl dicarbonate in 1,4-dioxane; water T=0 - 20°C;
参考文献
Pharmacia Italia S.p.A.
Patent: US2007/142415 A1, 2007 ;
Location in patent: Page/Page column 18 ;
US 20070142415 A1
反应条件
in dichloromethane Product distribution; Further Variations:Solvents;
参考文献
Tetrahedron Letters, , vol. 42, # 43 p. 7703 - 7705
反应条件
1: With chloroformic acid ethyl ester; triethylamine in tetrahydrofuran
T=-10°C; 0.166667 h;
2: in tetrahydrofuran; methanol
T=0 - 20°C; 3.33 h;
参考文献
Pharmacia Italia S.p.A.
Patent: US2007/142415 A1, 2007 ;
Location in patent: Page/Page column 18 ;
US 20070142415 A1