1: 2.) Cu(OAc)2, conc. aq. NH3, air / 1.) THF, Et2O, RT, 12 h, 2.) THF, Et2O, MeOH, 10 min 2: 62 percent / <N,N'-bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminato> manganese(III) chloride, di-tert-butyl peroxide, NaBH4 / toluene; ethanol / 12 h / Ambient temperature View Scheme

1: 2.) Cu(OAc)2, conc. aq. NH3, air / 1.) THF, Et2O, RT, 12 h, 2.) THF, Et2O, MeOH, 10 min 2: 1.) PbO2 / 1.) toluene, 5 min., irrad., 2.) toluene, from -78 deg C to RT, 1 h View Scheme

ammonium hydroxide; copper diacetate; air 1.) THF, Et2O, RT, 12 h, 2.) THF, Et2O, MeOH, 10 min; Yield givenMultistep reaction;