乙基2-异硫氰酸基-4,5-二甲基-3-噻吩羧酸酯合成路线 （共 5 条）
反应条件
1: 62 percent / CH2Cl2 / 1 h / Ambient temperature 2: 29 percent / N2H4*H2O / ethanol / 12 h / Heating View Scheme
参考文献
Santagati, Maria; Modica, Maria; Santagati; Russo; Spampinato
Pharmazie, 1996 , vol. 51, # 1 p. 7 - 11
反应条件
calcium carbonate in chloroform; water
T=0°C; 3.5 h;
参考文献
SENOMYX, INC.
Patent: US2008/306053 A1, 2008 ;
Location in patent: Page/Page column 67 ;
反应条件
in dichloromethane
T=20°C; 24 h;
参考文献
Santagati, Andrea; Granata, Giuseppe; Santagati, Maria; Cutuli, Vincenza; Mangano, Nunzio Guido; Caruso, Antonina
Arzneimittel-Forschung/Drug Research, 2002 , vol. 52, # 6 p. 448 - 454
参考文献
Ghorab, Mostafa M.; Ragab, Fatma A.; Noaman, Eman; Heiba, Helmy I.; Galal, Marwa
Arzneimittel-Forschung/Drug Research, 2006 , vol. 56, # 7 p. 553 - 560
反应条件
in dichloromethane
T=20°C; 0.25 h;
参考文献
Ghorab, Mostafa M.; Ragab, Fatma A.; Noaman, Eman; Heiba, Helmy I.; Galal, Marwa
Arzneimittel-Forschung/Drug Research, 2006 , vol. 56, # 7 p. 553 - 560
